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تم العثور علي : 10
 تم العثور علي : 10
  
 
إعادة البحث

Thesis 2020
Al-Kelesh, Kareem Hany Mohamed.
610 الطب والعلوم الطبية   610 الطب والعلوم الطبية  
So - to summarize our work - tibialis anterior transfer is a very successful operation for treatment of cases of dynamic foot supination with no significant complications. We found that the younger the patient - the better results post-operative and getting back to normal life faster. There is still a debate either total or split tendon transfer is better in these cases. However - latest researches say that total tendon transfer is better to avoid any
recurrence and avoid any loss of muscle power after transfer
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Thesis 2022.
Sherif Talaat Hamed Saad,
616 الأمراض  
Magnetic resonance imaging
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Thesis 2022.
Reham Fawzy Abdelwahab Elsherbiny,
617 الجراحة والموضوعات ذات الصلة  
Ophthalmology
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Thesis 2015
Ibrahim,Ibrahim Elsayed.
610 الطب والعلوم الطبية   610 الطب والعلوم الطبية  
Different methods and grafting materials have been used in tympanoplastic surgery. Grafting materials initially were of epidermal origin - and later various mesenchymal tissues were used.
Temporalis fascia and perichondrium remain the most commonly used materials. However - in certain conditions such as large perforations and revision tympanoplasty - fascia and perichondrium often undergo atrophy and subsequent failure in the postoperative period.
Fascia has been shown as a promising material in tympanoplasty. Although it is similar to cartilage and perichondrium as being mesenchymal tissue - it is more rigid quality tends to resist resorption and retraction.
Our study included 14 patients suffering from mucosal type of chronic suppurative otitis media with subtotal tympanic membrane perforations.
Audiological assessment was performed 3 months postoperatively. The cases were considered successful if the air-bone gap at the speech frequencies 500 - 1000 - 2000 - 4000 Hz was decreased 10-15db or less.
Comparing the present results with those of other researches using the same techniques - revealed that they are almost similar regarding success rate and graft taking
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Thesis 2016.
Abdeltawab Doaa.
617 الجراحة والموضوعات ذات الصلة  
Background: Regional analgesia has shown considerable promise in paediatric surgery.
Regional analgesia reduces opiate requirements - intraoperative general anaesthetic
requirements - improves recovery - and has a proven safety record. Ultrasonography
guidance improves the accuracy of the local anaesthetic placement and may further
increase safety. The two major types of regional analgesia are neuroaxial – epidural -
spinal or caudal – and peripheral. Peripheral nerve blocks avoid the potential for spinal
haematoma epidural infection.
Methods: The study involved two groups of patients who underwent abdominal
surgeries using midline or paramedian incisions; the RSB group (n=25) and the EPB
group (n=25).Both groups are comparable.
Results: The two groups had the same effect on pulse rate with no significant difference
between the two groups. The two groups had the same effect on pulse rate - however - the
MAP was significantly higher in RSB Group. The two groups had the same effect on
oxygen saturation with no significant difference between the two groups . The two
groups had the same effect on PEFR - however - it was significantly higher in RSB Group
Conclusion: We can conclude that rectus sheath block is as effective as epidural block in
reduction of pain intensity at rest and with coughing following major abdominal
operations in cancer patients. A single shot is effective up to 12 hours postoperatively.
Rectus sheath block is associated with hemodynamic stability along the 12 postoperative
hours with no drug- or procedure-related adverse events.
Keywords: regional - rectus sheath - epidural

Thesis 2013
Abdo,Ahmed Metwally
616 الأمراض  
Hematopoietic stem-cell transplantation (HSCT) offers a unique opportunity for long-term disease control to many patients with severe malignant or non-malignant - acquired or congenital disorders of the hematopoietic system - or with chemo-sensitive - radiosensitive or immuno-sensitive tumors. Stem cells from peripheral blood - bone marrow or cord blood are used as the graft product. HSCT has seen rapid expansion over recent decades. It is considered the treatment of choice in several circumstances - and it is integrated into the treatment algorithm for many disease categories from diagnosis.
Still - HSCT is associated with substantial morbidity and mortality. Patients and treating physicians face the challenge of deciding for or against a treatment with early risks of transplant-related mortality but the late benefit of long-term disease control. The dilemma increases when relatively non-toxic alternative therapies are available - even when their long-term benefit is yet unclear. However - most of complications could be predicted by proper assessment & so - could be prevented or at least decrease its severity.
Comorbidities are defined as any concurrent health condition or process that coexists with or may occur during the clinical course of a patient with a primary (index) disease or procedure that is being studied. Comorbidities can affect the moment of detection - prognosis - therapy and patient outcome in a variety of diseases.
Patients with liver dysfunction have an increased risk of developing early and late complications after hematopoietic stem-cell transplantation (HSCT). That’s why it is mandatory to evaluate liver status before transplantation in all cases. This evaluation should allow us to decide whether HSCT can be performed or whether we should adopt measures focused on preventing these complications. The evaluation of the liver in an HSCT candidate requires the collection of information by history-taking - physical examination - liver-function tests and - occasionally - imaging tests and liver biopsy. Additionally - as infection by hepatitis B or C viruses represents the most relevant cause of hepatic dysfunction after HSCT - the serological status of the patient should be carefully evaluated.
HBsAg + patients with an active hepatitis have an increased risk for VOD in the early phase after HSCT - recovery of cellular immunity 3-6 months after HSCT can result in HBV re-activation with a biochemical hepatitis that in up to 12% of cases can be fulminant.
Recommendations: If physical examination or LFTs suggest a chronic liver disease - try to perform a liver biopsy. If severe hepatic fibrosis or cirrhosis exists - HSCT using high-dose chemo-radiotherapy is contraindicated. If AST/ALT are normal; HSCT not contraindicated (no higher risk of VOD). If AST/ALT are increased; try to delay HSCT (increased risk of VOD).
In all cases test HBeAg - anti-HBe and HBV DNA:
a. All HBV DNA-positive patients should receive prophylactic antiviral therapy (lamivudine 100 mg/day orally during immunosuppression).
b. If HBV DNA-negative: monitor after HSCT and start antiviral therapy if becomes positive.
c. If pre-core mutant form (HBeAg - anti-HBe+‏ - HBV DNA‏+) there is increased risk of fulminant hepatic failure - so use prophylactic antiviral therapy.
In HBsAg- but anti-HBc+ and anti-HBs± patients; possible HBV reactivation is up to 20% of patients (reverse seroconversion). Recommendations are to test HBV DNA after HSCT and consider antiviral therapy if it becomes positive.
In HCV DNA + patients: some but not all authors have found association with HCV infection and VOD risk. Recovery of cellular immunity 3-6 months after HSCT can result in an HCV reactivation with biochemical hepatitis - but fulminant cases are exceptional. Although the long-term expected incidence of cirrhosis in these patients was considered low (<5%) - a long-term follow-up has shown an incidence of 24% at 20 years.
Recommendations: If physical examination or LFT suggest chronic liver disease - try to perform a liver biopsy. If severe hepatic fibrosis or cirrhosis exists; HSCT using high-dose chemo-radiotherapy is contraindicated. If there is chronic hepatitis with neither severe fibrosis nor cirrhosis; HSCT is not contraindicated. If AST/ALT are normal; HSCT is not contraindicated. If AST/ALT are increased; try to delay HSCT (increased risk of VOD) ; if it cannot be delayed ; consider treatment with ribavirin - interferon or peginterferon.
Cytomegalovirus (CMV) remains a major pathogen for solid organ transplant recipients - causing febrile syndromes - hepatitis - pneumonitis - retinitis - and colitis. Because CMV produces lifelong latent infection - differentiation of latent infection from active disease in immuno-compromised individuals presents a diagnostic challenge. All allogeneic bone marrow recipients are at risk for CMV pneumonia after HCT; however - the risk is highest in sero-negative recipients who receive marrow from a seropositive donor. Other risk factors include viral shedding from other sites - viremia - chronic steroid use - and GVHD. The use of sero-negative blood products and leukocyte–depleted platelets greatly reduces - but does not eliminate the risk of developing CMV pneumonitis in sero-negative recipients.
Although HSCT-associated cardiac toxicity has become less common in recent years using modern regimens - a wide range of incidences of mortality and morbidity are still being reported in small and large series of patients. As a general rule - an ejection fraction of ≥35-40% has been accepted as reasonable evidence of adequate cardiac reserve for HSCT. Ejection fraction does correlate weakly with survival and functional status; however - haemodynamic status - functional status - N-terminal pro-brain natriuretic peptide (NT-proBNP) and troponin are all independent predictors of prognosis and merit consideration when deciding who is fit for HSCT. Tissue perfusion - especially of the brain - correlates better with symptomatic status and biochemical markers of heart failure than ejection fraction.
Baseline pulmonary function tests should be performed prior to allogeneic HCT. A decreased diffusing capacity or an increased alveolar–arterial oxygen gradient - are independent risk factors for interstitial pneumonitis and for overall mortality after transplantation. Nevertheless - these findings alone should not preclude HCT - since they are less predictive of outcome than other factors - such as relapse status and the degree of donor–recipient HLA matching. Furthermore - there is no level of pulmonary function abnormality that is uniformly predictive of death - and many patients referred for allogeneic HCT have no other viable treatment options.
Age is a poor predictor of BMT outcome in both allogeneic and autologous transplantation. Pediatric patients may have a better outcome when compared to adults. Older adults may have a somewhat higher risk of transplant-related mortality than do younger adults. However - no study has definitively established a chronologic age at which the risk of the transplant is prohibitive. Age by itself should not be used as criteria to include or exclude a patient from Transplant.
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Thesis 2010
SHAFIE,WAFAA WAHBA MOHAMED
633 المحاصيل الحقلية والنباتية  
Wafaa Wahba Mohamed Shafie: Analysis of Gene Action for Yield and Quality characteristics in Diallel Crosses of Sesame. Unpublished Ph.D. Thesis - Department of Agronomy - Faculty of Agriculture - Ain Shams University - 2010. br Eight sesame genotypes were crossed in a diallel mating design - excluding reciprocals - to produce 28 F1 hybrid seeds in 2004 season and the 36 entries (8 parents + 28 F1’ s) were evaluated for eleven traits in 2005 season. The eight genotypes were re-crossed in the same diallel pattern in 2005 season and the 36 entries were evaluated for the same traits in 2006 season aiming to study heterosis - combing abilities - types of gene action and heritability - as well as correlation and path coefficient analysis for earliness - yield attributes and oil and protein contents in both seasons. br The results indicated that the mean squares due to all 36 genotypes as well as mean squares due to parents and crosses were highly significant for all studied characters - i.e - days to flowering - height of first capsule - plant height - fruiting zone length - number of fruiting branches/pant - number of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil and protein percentages in both seasons - revealing the presence of sufficient genetic variability in the studied genotypes. br Parents vs. crosses mean squares as an indication to average heterosis for all hybrids were significant in all traits. Significant desirable negative or positive heteosis relative to mid and better parents were observed in many crosses for all traits in both seasons. br Both general and specific combining ability mean squares were found to be highly significant for all studied traits in both seasons - indicating the importance of both additive and non-additive gene effects in the expression of the studied traits. The ratios of GCA/SCA variances were greater than unity for days to flowering in the first season and near unity in the 2nd - height of first capsule - plant height - fruiting zone length - no. of fruiting branches - no. of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil % and protein % in both seasons - indicating that the inheritance of these traits were mainly controlled by additive gene effects. However - ratios were less than unity for no. of capsules/plant in both seasons illustrating that this traits was mainly controlled by the non-additive gene effects. Good general combiner parents were identified for each of the studied traits. Some crosses exhibited significant desirable SCA effects in all studied traits and some of them involved at least one good general combiner parent - therefore - considered as promising F1 cross combinations for improving sesame traits. br High estimates of heritability values in the narrow sense exceeding 50% were detected for plant height - number of branches/plant - fruiting zone length - oil% and protein% in the two seasons. These values ranged -#102;-#114;-#111;-#109; 50.04% for number of branches/plant in 2005 season to 66.04% for oil % in 2006 season - indicating the importance of additive and additive x additive gene effects in the inheritance of these traits and consequently the effectiveness of selection for improving such traits in early segregating generations. However - moderate values of heritability in the narrow sense were obtained in both seasons for number of capsules/plant - capsule length - 1000-seed weight and seed yield/plant - ranging -#102;-#114;-#111;-#109; 32.67% for 1000-seed weight in the 1st season to 45.63% for seed yield/plant in the 2nd. With regard to the two earliness traits - i.e. days to flowering and height of first capsule - low estimates of narrow sense heritability were obtained in both seasons ranging -#102;-#114;-#111;-#109; 21.24% for days to flowering in the 2nd season to 27.49% for height of first capsule in the 2nd season - indicating that - in the case of moderate and low heritabilities in the narrow sense - response to selection for these traits in later segregating generations would be expected. br Except for oil% - the other 10 earliness - yield attributes and protein content exhibited consistent high estimates of broad sense heritabilities as compared to their respective narrow sense values ranging -#102;-#114;-#111;-#109; 84.6% for 1000-seed weight in 2005 season to 99.4% for height of first capsule in both seasons - indicating that dominance effects had prominent role in the inheritance of these traits. br Path analysis indicated that - plant height - fruiting zone length - height of first capsule and no. of capsules/plant and their interactions a crosse as the main sources of seed yield variation br . br Key Words: Sesame - Diallel crosses - Combining abilities - Heritability - Earliness - Yield - Oil - Protein - Correlation and path analysis. br Heterosis estimates - Wafaa Wahba Mohamed Shafie: Analysis of Gene Action for Yield and Quality Characteristics in Diallel Crosses of Sesame. Unpublished Ph.D. Thesis - Department of Agronomy - Faculty of Agriculture - Ain Shams University - 2010.
Eight sesame genotypes were crossed in a diallel mating design - excluding reciprocals - to produce 28 F1 hybrid seeds in 2004 season and the 36 entries (8 parents + 28 F1’ s) were evaluated for eleven traits in 2005 season. The eight genotypes were re-crossed in the same diallel pattern in 2005 season and the 36 entries were evaluated for the same traits in 2006 season aiming to study heterosis - combing abilities - types of gene action and heritability - as well as correlation and path coefficient analysis for earliness - yield attributes and oil and protein contents in both seasons.
The results indicated that the mean squares due to all 36 genotypes as well as mean squares due to parents and crosses were highly significant for all studied characters - i.e - days to flowering - height of first capsule - plant height - fruiting zone length - number of fruiting branches/pant - number of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil and protein percentages in both seasons - revealing the presence of sufficient genetic variability in the studied genotypes.
Parents vs. crosses mean squares as an indication to average heterosis for all hybrids were significant in all traits. Significant desirable negative or positive heteosis relative to mid and better parents were observed in many crosses for all traits in both seasons.
Both general and specific combining ability mean squares were found to be highly significant for all studied traits in both seasons - indicating the importance of both additive and non-additive gene effects in the expression of the studied traits. The ratios of GCA/SCA variances were greater than unity for days to flowering in the first season and near unity in the 2nd - height of first capsule - plant height - fruiting zone length - no. of fruiting branches - no. of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil % and protein % in both seasons - indicating that the inheritance of these traits were mainly controlled by additive gene effects. However - ratios were less than unity for no. of capsules/plant in both seasons illustrating that this traits was mainly controlled by the non-additive gene effects. Good general combiner parents were identified for each of the studied traits. Some crosses exhibited significant desirable SCA effects in all studied traits and some of them involved at least one good general combiner parent - therefore - considered as promising F1 cross combinations for improving sesame traits.
High estimates of heritability values in the narrow sense exceeding 50% were detected for plant height - number of branches/plant - fruiting zone length - oil% and protein% in the two seasons. These values ranged from 50.04% for number of branches/plant in 2005 season to 66.04% for oil % in 2006 season - indicating the importance of additive and additive x additive gene effects in the inheritance of these traits and consequently the effectiveness of selection for improving such traits in early segregating generations. However - moderate values of heritability in the narrow sense were obtained in both seasons for number of capsules/plant - capsule length - 1000-seed weight and seed yield/plant - ranging from 32.67% for 1000-seed weight in the 1st season to 45.63% for seed yield/plant in the 2nd. With regard to the two earliness traits - i.e. days to flowering and height of first capsule - low estimates of narrow sense heritability were obtained in both seasons ranging from 21.24% for days to flowering in the 2nd season to 27.49% for height of first capsule in the 2nd season - indicating that - in the case of moderate and low heritabilities in the narrow sense - response to selection for these traits in later segregating generations would be expected.
Except for oil% - the other 10 earliness - yield attributes and protein content exhibited consistent high estimates of broad sense heritabilities as compared to their respective narrow sense values ranging from 84.6% for 1000-seed weight in 2005 season to 99.4% for height of first capsule in both seasons - indicating that dominance effects had prominent role in the inheritance of these traits.
Path analysis indicated that - plant height - fruiting zone length - height of first capsule and no. of capsules/plant and their interactions a crosse as the main sources of seed yield variation
.
Key Words: Sesame - Diallel crosses - Combining abilities - Heritability - Earliness - Yield - Oil - Protein - Correlation and path analysis.
Heterosis estimates
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Thesis 2009
MOHAMED ABDEL-BASET،REDA
630 الزراعة   630 الزراعة  
I. Establishment stage:
Sterilization treatments had a non significant effect on survival% of
Paulownia explants. However - the combined treatment with mercuric
chloride + clorox gave the highest survival% - while clorox achieved the
lowest value.
A spontaneous rooting occurred in the establishment stage on
Paulownia explants. The effect of explant type was significant on shoot
length - fresh weight of shoots - number of roots and root length of
Paulownia. Values of these characters were significantly higher when
explants were excised with a piece of callus - compared to those without
callus. The effect was insignificant concerning the total number of shoots
and total number of leaves.
A significant effect was exerted by MS strength on shoot length - total
number of leaves - number of roots and root length. The highest values of
these parameters were achieved on the normal strength of MS medium.
Values of total number of leaves produced on ½MS and 1½MS besides
number of roots on 1½MS are significantly among the highest ones.
Values of the above-mentioned four characters declined significantly to
the lowest category when explants were inoculated on MS medium at
double strength (2MS). The effect of MS strength on Paulownia explants
was insignificant concerning the total number of shoots and fresh weight
of shoots.
The interaction between explant type and MS strength had a significant
effect. When explants with a piece of callus were inoculated on MS
medium - root length was the highest - or on 1½MS medium - both number
of roots and root length were significantly the highest - . Insignificant
effects were exerted by this interaction on total number of shoots - total
number of leaves - shoot length and fresh weight of shoots
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Thesis 2003
Mona Magdy Halim Eskender
616 الأمراض  
” The present study is a retrospective study done on 326 patients of prostate cancer in Mansoura University Hospital and Urology and Nephrology center during the period between January 1990 to January 2000.
” Our study revealed that prostate cancer was common among patients over the age of 65 years (50.9%) and in those with no family history. Smokers represented 35.3% of our patients. The commonest presenting symptom in our patients was urine retention (89.6%) - to less extent bony aches and dysuria (59.2% for each) - while hematuria and frequency were less common presenting complaints.
” Among 326 patients included in our study - only 226 patients received treatment and had adequate follow-up data. Thirty patients received radical prostatectomy - 22 patients received radical radiotherapy with hormonal cytoreduction - 156 patients received hormonal treatment (subcapsular orchidectomy and/or antiandrogen therapy) and 18 patients received other treatments.
” Using multivariate analysis of different predictors of response rate in patients with prostate cancer - it was found that lines of treatment were the most statistically significant predictor of response rate followed by pathological type then clinical stage at time of presentation - while the most significant predictors of overall survival rate were lines of treatment and pathology - followed by clinical stage. However - lines of treatment - pathology and clinical stage had equal statistical significance in predicting progression free survival rate in patients with prostate cancer.
” Health education programs about risk factors of prostate cancer - screening techniques as well as effective therapeutic modalities are recommended
MANSOURA UNIVERSITY

Thesis 1998 .
El-Gouhary, Ahmed Ali Ali
Ain Shams University. faculty of Medicine. General Surgery Department,

 







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