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Abstract
Vesicovaginal fistula present as a debilitating and stressful condition for women not only in developing countries but as well in other parts of the world.
The first recorded reference of vesicovaginal fistulae were made in 1550 BC in ancient Egypt.
The etiology of vesicovaginal fistula differs according to the economic state of the countries, where the obstetric labour is the main cause of etiology in developing countries, as a complication of pelvic surgery in non-developing countries. All these factors lead to presence of more than 2 million women complaining of fistula with an increase from 50,000 to 100,000 new cases every year according to the latest records of the world health organization.
Urethrocutaneous fistula is the commonest complication of hypospadias repair. Several factors appear to be important in the development of a fistula; these include loss of vascularity, choice of the surgical technique, efficacy of the surgeon and never the less; postoperative care to prevent the infection.
The concept of biological glue was first introduced in the clinical care 60 years ago during the Second World War. Although its concept was new and unique; its application proved to be disappointing due to the transmission of infection.