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Abstract - 73 - SUMMARY AND CONCLUSION Ethyl alcohol is a volatile and flammable liquid which enters in many beverages. Its concntration in these beverages differes from one drink to It is least in beer 2-5%. It is easly absorbed from the mucous membrane. Hince another. about 20% are absorbed from the stomach and the intestinal tract absorbs the remainder. Ethanol is oxidized in the liver into acetaldehyde by enzyme alcohol dehydrogenase (ADH), then acetic acid and lastly CO2 and water. Hence metabolic acidosis may occur. Ethanol intoxication may be harmful to almost any system. However, it affects mainly the C.N.S and the liver. The central nervous system effects include acute behavioural changes involving acute alcoholic intoXication, alcoholic coma, withdrawal syndromes, nutritional disorders and consequences of alcoholic liver diseases. ---- ---- - 74 - Acute behavioral changes involve acute intoriction, alcoholic coma, hang over and amnestic episodes. Acute Alcoholic intoxication may occur with blood alcohol level as low as IOOmg/IOOmI and death may occur at blood alcohol level 40Omg/IOOmI. It may reach high up to TOOmg!IOOmI. in alcoholics. There is a wide spectrum of manifestations of alcohoI with drawal ranging from anxicty and tremulocuness to full blown delerium tremenes. The later is an acute organic psychosis that is usually manifested within 24-72 hours after the last drink.Chronic use of alcohol produces nutritional defeciencies resu1ting in certain characteristics C.N.S manifestations. The most common of these are alcoholic dementia, Wernicke’s encephalopathy, Korsakoff’s psychosis and alcoholic polyneuropathy. Wernicke’s encephalopathy is manifested by ataxia ophthalmoplegia and mental confusion, It is an acute disorder due to thiamine deffeciency. It may be followed by Korsakoff’s psychosis where the cloudness of consciousness anterograde and retograde amnesia. The effects of alcohol on the liver result not only |