الفهرس 
AIDS definitionOnly 14 pages are availabe for public view
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Abstract
Acquired immune deficiency syndrome (AIDS) was first recognized in 1981 and it was well documented that AIDS is caused by a virus of retroviridea family called human immune deficiency virus (Fly).The WHO estimates at 1997 that over 20 million adults and 1.5 million children have been infected with HIV since the pandemic began 20 years ago.HIV can be transmitted in children by blood and blood products but vertical transmission from the mother to her infants is the most common route of transmission in the pediatric age group.Both thalassaeniics and hemophilics are at high risk of the disease because of receiving multiple transfusions (blood and blood products e.g. factor VIII concentrate) that may be contaminated with the virus.For some time it has been known that allogeneic blood transfusions have many immunological effects on recipients affecting both humoral and cellular immunity. These immunological abnormalities may closely simulate those occurring in AIDS.AIDS causes many immunological features including leucopenia, lymphopenia, abnormal T and B cell count and activity, impaired natural killer cell activity and others.The present study was carried out to throw some light on the possibility of HIV infection among Egyptian f3-thalassemia major and hemophilic children. Also our aim was to evaluate the immune state of