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Abstract Omega-3 fatty acids have an anti-inflammatory property. The benefit of( n-3 PUFA) Polyunsaturated Fatty Acids supplementation has been documented in animal models of periodontal inflammation and a trend towards reduced inflammation has been seen in human experimental gingivitis. The purpose of this study was to examine the potential anti-inflammatory effects of PUFA supplementation, by administration of omega-3 capsules (300mg) twice daily for the test group patients along six months.20 patients selected for this study (10 who receive omega-3 plus periodontal surgery on one side and conventional periodontal therapy on the other side) (10 patients who subjected to periodontal surgery on one side while the other side subjected to conventional periodontal therapy without taken omega-3 capsules ). After one week from the screening and preparation of the patients then the test group patients and control group patients undergo periodontal surgery on one side and conventional therapy on the other side (S & RP). The clinical parameters and radiological measurements have been evaluated and measured along the study period which is 6 months. The clinical parameters (PI, GI, PPD, CAL and BOP) decreased significantly as well as the rate of bone resorption decreased but minimally. Consequently, omega-3 fatty acids may provide new insight and safe adjunctive to the nonsurgical periodontal therapy in patients with chronic periodontitis. |