الفهرس | Only 14 pages are availabe for public view |
Abstract Bacterial contamination of blood components is currently the most frequent infectious complication of blood transfusion. The incidence of bacterial contamination of whole blood units ranges from 0.1% to 2.8 %. The most frequent bacteria species that contaminate whole blood are usually found to be common skin flora. The most common risk factors of bacterial contamination of blood units include introduction of bacteria through the phlebotomy site due to defect of sterilization during collection procedures, which is the most common risk factor. The receiving of bacterially contaminated blood units is presented with transfusion reaction. The severity of the reaction ranges from no reaction to fatal septic shock . The contaminated units can be detected by staining and microscopic examination of a smear immediately prior to transfusion, blood culture on day 2 or 3 of storage, measurement of glucose and pH in blood unit using a reagent test strip. Bacterial contamination of blood units can be greatly reduced by implementation of infection control program. The accuracy of laboratory analysis of the clinical specimens and microbial isolates depend on implementation of quality assurance program, that assesses the quality of the specimens, documents the validity of the test methods, monitors the performance of test procedures, reagents, media, instruments and reviews test results for errors. So, implementation of quality control program in microbiological laboratory is very important and has a great effect on the performance of the laboratory, and hence greatly produces the reliable and the accurate results of any performed tests. |