الفهرس 
Introduction and aim of workOnly 14 pages are availabe for public view
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Abstract
•The present study is a retrospective study done on 326 patients of prostate cancer in Mansoura University Hospital and Urology and Nephrology center during the period between January 1990 to January 2000.
•Our study revealed that prostate cancer was common among patients over the age of 65 years (50.9%) and in those with no family history. Smokers represented 35.3% of our patients. The commonest presenting symptom in our patients was urine retention (89.6%), to less extent bony aches and dysuria (59.2% for each), while hematuria and frequency were less common presenting complaints.
•Among 326 patients included in our study, only 226 patients received treatment and had adequate follow-up data. Thirty patients received radical prostatectomy, 22 patients received radical radiotherapy with hormonal cytoreduction, 156 patients received hormonal treatment (subcapsular orchidectomy and/or antiandrogen therapy) and 18 patients received other treatments.
•Using multivariate analysis of different predictors of response rate in patients with prostate cancer, it was found that lines of treatment were the most statistically significant predictor of response rate followed by pathological type then clinical stage at time of presentation, while the most significant predictors of overall survival rate were lines of treatment and pathology, followed by clinical stage. However, lines of treatment, pathology and clinical stage had equal statistical significance in predicting progression free survival rate in patients with prostate cancer.
•Health education programs about risk factors of prostate cancer, screening techniques as well as effective therapeutic modalities are recommended.