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Abstract Orthotopic bladder substitution has gained wide acceptance after radical cystectomy in the last decade. Different bowel segments with different configurations have been utilized to construct intestinal neobladder. However, it is universally accepted that detubularization and reconfiguration provides the best urodynamic features of the reservoir. In spite of this fact, 20-30% of patients suffers from nocturnal enuresis. .Fifty patients (25Kock and 25 W neobladder) were evaluated by urine cultures, ascending pouchography, micturating cysto-urethrography and urodynamic studies using uroflowmetry and filling cystometry (this cystometry was done while the patients were fasting and 2 hours after feeding). The only one significant change in our results was the reduction in maximum enterocystometric capacity. This reduction in capacity was statistically significant when calculated for the total (Fasting- .:f:.539.1.:f:.155.7& Post-prandial = 495.9:t146.2). Continent (Fasting= 538:!:. 177 &post-prandial= 505:!:. 168 .5)&enuretic patients «Fasting= 539:!:.177&post-prandial=481:!:.106.8). It was highly significant in the enuretic group implying significant contribution of this finding to the pathogenesis of nocturnal enuresis in such patient,s. It was also noted that, the frequency and amplitude of unhibited contractions were constantly increased postporandially but not reaching i statistical significance: The pressure at mid-capacity and at maximum capacity showed constant lowering in the post-prandial states but not to a t statistical significance. On the other hand, the onset and the duration of these contractions were comparable during the fasting and post-prandial states. |