الفهرس | Only 14 pages are availabe for public view |
Abstract The most common type of congenital vascular malformation is venous malformation (VM), having an incidence rate of 2 in 10,000 and a prevalence of 1%. Often it leads to severe pain and discomfort to patients as well as morbidity and serious local and systematic complications. Different sclerosants have been used for VM including polidocanol, ethanol, sodium tetradecyl sulfate, and cyanoacrylate. Ethanol has been associated with the lowest incidence of lesion re-expansion and therefore is suggested as the most effective and first choice for sclerosing agent. The aim of our study was to compare the success rate of different used sclerosing agents (ethanol, cyanoacrylate, and polidocanol foam) in treatment of low flow vascular malformations. Sixty patients with definitive diagnosis of low flow vascular malformation, were included in this study, and were divided into 3 equal groups: All patients were followed-up within 6 months of treatment by clinical examination and detailed duplex u/s examination and all complications were recorded with evaluation of outcome (success and partial failure). Results showed that Polidocanol is a safer sclerosing agent compared to ethanol and Cyanoacrylate. The utilization of polidocanol alone, or in combination with other agents, for the treatment of VMs can lead to good efficacy. However, ethanol was associated with better cure rate than polidocanol and Cyanoacrylate. Cyanoacrylate was associated with sufficient cure rate but complicated by hard mass so better to be used pre-operative. |