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العنوان
Effect of heparin reversal by protamine sulfate on the outcome of thrombolysis in acute ischemic stroke after percutaneous coronary intervention/
المؤلف
Fawzy,Khaled Fayez
هيئة الاعداد
باحث / خالد فايز فوزي المنسى
مشرف / هاني محمد عارف
مشرف / عزة عبد الناصر عبد العزيز
مشرف / أحمد على إبراهيم البسيوني
مشرف / عماد عفت فخري شحاته
تاريخ النشر
2024
عدد الصفحات
138.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
1/1/2024
مكان الإجازة
جامعة عين شمس - كلية الطب - Neurology
الفهرس
Only 14 pages are availabe for public view

from 138

from 138

Abstract

Acute ischemic stroke is an uncommon but often major complication of percutaneous coronary intervention (PCI) with a major impact on mortality and morbidity post-PCI.
Independent predictors of stroke following PCI include age, female sex, and prior history of stroke or transient ischemic attack (TIA)
The relative risk of stroke is elevated during the first 2 days and then declined gradually at 4 to 8 weeks after PCI.
The primary ischemic mechanism of PCI stroke is embolization rather than hemodynamic instability. proximal embolism mostly affecting the MCA territory caused the majority of radiologically confirmed ischemic strokes after PCI
According to current guidelines, the Administration of IV tissue plasminogen activator(tPA) is the recommended standard of care in acute ischemic stroke during the first 4.5 hours from stroke onset. However, they exclude intravenous IVT in heparinized patients with an activated partial thromboplastin time (aPTT) greater than 40 seconds
As a result, there are no current guidelines for the management of patients who develop stroke after PCI.