الفهرس 
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Abstract
Aim: To evaluate the tumor associated micro-environment including micro-vessel Density,
macrophages and mast cells, eosinophils in conventional and unicystic ameloblastic lesions.
Methodology: 22 specimens of ameloblastoma distributed equally between the study groups,
conventional and unicystic ameloblastoma were retrieved from the Oral and Maxillofacial Pathology
Department, Faculty of Dentistry, Cairo University. Micro vessel density using CD34 and the number
of macrophages, mast cells and eosinophils demarcated by CD68, toluidine blue, congo-red respectively
were assessed.
Results: The mean of blood vessels, mast cells and eosinophils were higher in conventional
ameloblastoma than uni-cystic ameloblastoma with statistically significant difference except for
eosinophils than was statistically insignificant. The mean value of macrophages count was higher in unicystic ameloblastoma than conventional ameloblastoma with statistically significant difference.
Moreover, there was no statistically significant correlation between blood vessel density and
eosinophils, mast cells, macrophages in either of the groups.
Conclusion: The significant difference in the connective tissue elements between the studied
groups suggests that tumor associated microenvironment has a crucial role in the diverse behavior
of different types of ameloblastoma
Keywords: ameloblastoma(AB), mast cells(MCs), blood vessels(BVS),
Mean Vascular Density(MVD).