الفهرس 
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Abstract
Summary
Allergic rhinitis (AR) is known as a non-infectious inflammatory disease of the nasal mucosa, and it has clinical symptoms of sneezing, rhinorrhea, nasal congestion and itching. Its development is mediated by IgE mainly after the body has contact with an allergen, and it involves many types of cell factors and inflammatory factors
The aim of this study was to evaluate the efficacy of in office posterior nasal nerve cauterization in treatment patients with persistent allergic rhinitis and the main objective was to evaluate the efficacy of in office posterior nasal nerve electrocauterization in treatment of patients with persistent allergic rhinitis in ”SCU” hospitals.
A prospective interventional study was conducted outpatient clinic of Suez Canal university hospitals in the period from August 2022 to August 2023.
Adult patients with moderate to severe persistent allergic rhinitis not responding to medical treatment were recruited. Patients were followed-up and assessed by a reflective Total Nasal Symptoms Score (rTNSS) at 1 week & 1 month,3months, 6months after the procedure, for reassessment of nasal symptoms and comparison with pre procedure symptoms, endoscopic nasal exam was done each time, assessment for presence of any complications and rQOL 6 months post procedure.
In the present study, fifty-five patients complained from moderate to severe allergic rhinitis with mean age 29.5± 7.6 years and median of 29 years ranged from 19 to 52 years. The males were representing 63.6% and 36.4% females.
In the current studythe pre-procedure total mean score was 9.9± 1.1. It was improved after 1 week from procedure (9.9± 1.1 vs. 8.5± 0.9, p <0.001),after 1 month (9.9± 1.1 vs. 5.8 ± 1, p <0.001), after 3 months (9.9± 1.1 vs. 3.9± 1.6, p <0.001) and after 6 months from procedure (9.9± 1.1 vs. 3.9± 1.6, p <0.001). The mean total rTNSS did not improve after 6 months when compared to results after 3 months. Also, there was a marked decrease in all subdomain symptoms.
In this study, the mean total preprocedural rQOL was 100.4± 9.3 and the median was 101 ranging from 83 to 127. After 6 months from the procedure the total rQOL mean score was 28.7± 4.2 and ranged from 20 to 40 with a median of 29.
This study agreed that electrocauterization showed mild adverse events as only one patient experienced minimal epistaxis and needed no intervention. Forty patients (72.7%) had mild facial pain or discomfort and only needed analgesics. All patients had crustations and only one patient showed sinusitis.
This study concluded that office-based electrocauterization of posterior nasal nerve is considered a safe and effective method in treatment of persistent allergic rhinitis. It offers a good improvement of nasal symptoms and quality of life for patients with allergic rhinitis. Office-based electrocauterization of posterior nasal nerve reaching the most improvement of nasal symptoms within 3 months of procedure. Office-based electrocauterization of posterior nasal nerve was well tolerated by all treated patients who experienced only minimal discomfort and crustations during and post-procedure.