الفهرس 
NEONATAL SEPSISOnly 14 pages are availabe for public view
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Abstract
Background: Non-alcoholic fatty liver disease (NAFLD), is an abnormal accumulation of fat in the liver in the absence of secondary causes of fatty liver that is associated with metabolic comorbidities including cardiovascular disease (CVD). Recently, carotid plaque can predict future cardiovascular events.
Objective: This study aimed to determine the association between NAFLD and subclinical carotid atherosclerosis.
Subjects and methods: This cross-sectional study was conducted on 120 subjects categorized into two groups; group I: 80 patients diagnosed as NAFLD who were further subdivided into two subgroups: 43 NAFLD patients with normal carotid intima medial thickness (CIMT), and 37 NAFLD patients with increased CIMT. group II: 40 patients without NAFLD.
Results: ALT, AST, INR, and urea were significantly higher in NAFLD patients with significantly deceased hemoglobin level, and direct bilirubin compared to non-NAFLD patients (p-value < 0.05). There were highly statistically significant increased cholesterol, triglycride, LDL, and HDL levels in NAFLD patients (237, 160, 151, and 51, respectively) compared to non-NAFLD patients (120, 104, 55.4, and 33.5, respectively) (p-value < 0.001). there were highly statistically significant increase in CIMT and percentage of increased CIMT thickness in NAFLD patients compared to non-NAFLD patients (p-value < 0.001) with a significant correlation between decreased platelets, increased albumin, and decresed PC level and increased CIMT thickness (p=0.003, 0.003, and 0.001, respectively) in NAFLD group.
Conclusions: Patients with NAFLD have significantly higher mean CIMT values, representing a possible increased risk of atherosclerosis that was associated with low platelets, high albumin and low prothrombin concentration.