الفهرس | Only 14 pages are availabe for public view |
Abstract Age-related macular degeneration (AMD) is a medical condition which may result in blurred or no vision in the center of the visual field. Early on there are often no symptoms. Over time, however, some people experience a gradual worsening of vision that may affect one or both eyes. Spectral domain optical coherence tomography SD-OCT is a noninvasive imaging technique, able to visualize structural changes of the neuro sensory retina and the retinal pigment epithelium RPE. OCT is used to support the initial diagnosis of CNV obtained from FA and ICGA and to detect early signs of CNV activity, such as subretinal fluid, intraretinal cystoid spaces, and pigment epithelium detachment PED. Intravitreal injection is the standard method of administration, of antivascular endothelial growth factor Anti-VEGF which block its interaction with receptors on the endothelial cell surface and so retard or reverse vessel growth. They have become the predominant means of treatment for CNV, dramatically improving the visual prognosis. Our prospective quasi- experimental study was carried out on 30 eyes of patients with neovascular ARMD at the Ophthalmic Outpatient Clinic at Suez Canal University Hospital, to monitor the response of CNV to Anti-VEGF to more efficient follow up and better visual outcome in this patient’s category. Including, age group: 5o years and above, of both sexes, with stablished diagnosis of AMD neovascularization using fluorescein angiography and spectral domain OCT, and only with clear identification of the morphology and extent of neovascularization on OCTA were enrolled in this study. 86 Excluding patients with history or clinical evidence of diabetic retinopathy, any significant media opacity that could affect image quality, myopia greater than 6 diopters, glaucoma and other hereditary, inflammatory and/or vascular chorio |