الفهرس | Only 14 pages are availabe for public view |
Abstract Polycystic ovary syndrome (PCOS) is considered the most common endocrine disorder in reproductive age in females. PCOS is characterized by reproductive and metabolic disturbances. Androgen excess is a hallmark of PCOS, driving many of the phenotypic features. It was estimated that about 75% of these females with PCOS have an impairment of insulin action, as measured by gold standard methods. Although its exact etiology is unclear, PCOS is currently thought to emerge from a complex interaction of genetic and environmental factors, the pathogenesis of PCOS has been related to altered luteinizing hormone (LH) action, insulin resistance and predisposition to hyperandrogenism. |