الفهرس | Only 14 pages are availabe for public view |
Abstract Low back pain from lumbar disc prolapse (LDP) or spinal stenosis is frequent in degenerative lumbar spine conditions. The intervertebral discs start the degenerative process, which causes pathologic changes in the ligaments, vertebral bodies, posterior bulging of the disc, narrowing of the central spinal canal, osteophyte development, and vertebral body sliding. Posterior lumbar interbody fusion (PLIF) is used to treat symptomatic spondylolisthesis, degenerative scoliosis, and spinal stenosis caused by instability. PLIF stabilizes the lumbar spine, restores disc height, and mechanically decompresses the dural sac and nerve roots. Interbody fusion removes the intervertebral disc and implants graft material between the vertebral bodies. The interbody fusion cage maintains foraminal height, prevents recompression, and is filled with biological contents. BMA reduces harvest site morbidity and is less invasive than iliac crest bone graft. MSCs, osteoblast progenitors, immune-regulatory, angiogenic, and anti-apoptotic trophic factors are also found there. Our work augments the local bone graft obtained after decompression with BMA to boost its osteogenic ability and bone fusion chances. PLIF was recommended for 64 individuals with lumbar instability or canal stenosis in this prospective analysis. 32 patients underwent single-level posterior lumber interbody fusion (PLIF) with local bone graft and bone marrow aspirate (BMA). 32 patients underwent single-level posterior lumber interbody fusion (PLIF) with local bone graft without bone marrow aspirate (BMA). |