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العنوان
Value of MRI in early detection and evaluation of hemophilic arthropathy; correlation with clinical evaluation /
المؤلف
Abdelrahman, Doaa Abdelhakim Mahmoud.
هيئة الاعداد
باحث / دعاء عبد الحكيم محمود عبد الرحمن
مشرف / محمد فرغلي امين
مشرف / جيهان لطفي عبد الحكيم
مناقش / احمد سيد ابراهيم عيسى
مناقش / هويدا عبد الحكيم نفاذى
مناقش / منال فايز أبو سمرة
الموضوع
Joints - Magnetic resonance imaging. Joints - injuries.
تاريخ النشر
2023.
عدد الصفحات
107 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
30/8/2023
مكان الإجازة
جامعة المنيا - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

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from 114

Abstract

Hemophilic arthropathy is the most common complication in patients with hemophilia. If not properly treated and controlled in the beginning, it could develop into a crippling condition that eventually necessitates extensive surgery, such as total joint arthroplasty. Objective imaging diagnosis rather than subjective evaluation is crucial, preventing over- or under-treatment.
The aim of the work is to evaluate the value of MRI in evaluation and early detection of joint affection in hemophilic patients in correlation with their clinical presentation. And to assess the role of T1 3D FFE MRI sequence in hemosiderin deposition and cartilage degeneration in hemophilic joints.
All patients were subjected to Proper history
Assessment of musculoskeletal function of the joints using HJHS version 2.1 which was assessed in all patients by a hematology doctor and a rheumatology physician.
Assessment of the MRI score of the examined joints was performed in all patients using IPSG MRI scale.
US and X-ray were done to evaluate Joints in some patients.
There was a strong positive correlation between hemophilic joint score and IPSG MRI score in symptomatic joints while There was no significant correlation between HJHS and IPSG MRI score among asymptomatic joints.
The T13D FFE sequence is better for detection of hemosiderin and cartilage degeneration in asymptomatic joints than in symptomatic group.

Conclusion
The imaging and clinical modalities that are currently accessible for detecting and monitoring musculoskeletal disorders play varied and often have complementary roles in the evaluation of arthropathy in people with hemophilia.
Pathological abnormalities in asymptomatic joints that seem normal on clinical evaluation can be found with MRI. As arthropathy progresses, the role of clinical examination increases to assess the disease severity.
Adding the 3DT1FFE MRI sequence is needed for detection of early arthropathic changes and its efficiency in asymptomatic joints rather than in cases of advanced arthropathy.
Recommendation:
We recommend to solidify our knowledge by studying a larger number of patients and using the value of US examination in further studies with a larger number of patients to get benefit from its advantages in evaluation of hemophilic joints, in addition, to using recent MR mapping in evaluation of articular cartilage.