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Abstract Introduction: Abnormal fetal growth is associated with perinatal and maternal risks. Fetal macrosomia for example, is associated with prolonged labor, shoulder dystocia, brachial plexus palsy, birth canal injuries and postpartum hemorrhage. While fetal growth restriction can result in neonatal morbidity and intrauterine fetal death Objectives: The aim of this study was to correlate fetal abdominal subcutaneous tissue thickness (FASTT) measured by transabdominal ultrasound and birth weight measured immediately after delivery and to obtain cut-off values for FASTT to predict small and large for gestational age babies in the Egyptian population. Patients and Methods: This was a prospective cohort study conducted in Ain Shams University Hospitals according to the stipulations of ASU ethical and scientific committee. An informed written consent was obtained from all study subjects after explaining the procedure details and prior to inclusion in this study. The privacy of participants and confidentiality of data was guaranteed throughout the study. Results: A total of 86 pregnant women between the ages of 20 and 35 years with gestational ages between 24 to 40 weeks and BMI ranging between 17.9 to 29.3 were included in this study. 67.4% of pregnant women gave birth via cesarean section (CS) and 32.6 % gave birth via normal vaginal delivery (NVD). 54.7% of the newborns were females, while 45.3% were males. Conclusion: FASTT can be used as a predictor for birth weight; it is a better indicator of LGA than SGA.FASTT can be incorporated into fetal weight estimation formulas as a method to increase its accuracy especially at birth weight extremes. A study on a larger scale of Egyptian population should be conducted to generate fetal weight estimation formulas based on the Egyptian ethnicity to be the reference for medical practice in Egypt |