الفهرس | Only 14 pages are availabe for public view |
Abstract Timely reperfusion of the infarct-related coronary artery using percutaneous coronary intervention (PCI) is central to optimal ST-segment elevation myocardial infarction (STEMI) treatment, reducing infarct size, minimizing myocardial damage, preserving ventricular function, and decreasing morbidity and mortality(233). Therefore, heart failure (HF) is considered a severe complication of acute ST-segment elevation myocardial infarction (STEMI), and it occurs frequently after acute anterior wall STEMI due to the larger infarct size. (284). Total ischemic time should be the real target for improving mortality in STEMI patients. Any delay to reperfusion may adversely influence patient outcomes and should therefore be minimized. Clinical trials should focus on diminishing the total ischemic time and its impact on the incidence of shock and other adverse cardiovascular events upon arrival to the hospital (248) Aim of the work is to study the relationship between time delay in patients with anterior STEMI undergoing primary percutaneous coronary intervention and the occurrence of heart failure during the hospital stay. A total of 100 consecutive patients with acute anterior wall STEMI were recruited from Cardiology department in Tanta University hospital prospectively included in this study. Ultimately, the patients were divided into two groups: group 1: patients treated by primary PCI without development of heart failure.group 2: patients treated by primary PCI with development of heart failure , the study was done April 2022 to April 2023. The major finding of the present study is that every minute of delay in treatment of patients with STEMI does affect mortality and was associated with higher in-hospital AHF . consequently , the current study strongly support that TIT can be a good quality measure and other clinical determinants in order to improve survival in STEMI patients. Hence, attempts should be made to shorten TIT in order to enhance patients‘ survival (258). |