الفهرس 
HEADACHE OVERVIEWOnly 14 pages are availabe for public view
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Abstract
Background: Headache is one of the most common disorders of the central nervous system and causes multiple levels of dysfunction. One of the most underestimated types of headaches is headaches due to CSF dysregulation disorders either idiopathic intracranial tension or spontaneous intracranial hypotension.
Aim of the Work: Measurement of the prevalence of CSF dysregulation-related headaches in a hospital-based headache population, assessment of the demographic data of a group of headache patients, assessment of the correlation between CSF dysregulation headache and BMI, assessment of the correlation between CSF dysregulation-related headache and fundus examination, assessment of the correlation between CSF dysregulation-related headache and MRI brain& MRV findings and assessment of the correlation between IIH and optic nerve sheath diameter ONSD assessment by trans orbital sonography TOS.
Patients and Methods: In our observational study, conducted between 1 November 2022 and 30 April 2023, at the headache clinic of Ain Shams University hospitals, we studied the prevalence of IIH among the headache population, demographic characteristics, sleep quality, MRI brain findings suggestive of IIH, fundus examination, opening pressure reading values, and efficiency of USG in the evaluation of patients with IIH.
Results: Among the 168 headache patients, IIH prevalence came out to be 30.35%, IIH patients had higher age, with site of headache being vertical in most of cases, higher BMI, with the character of headache being throbbing in most cases. We found that the empty sella turcica sign has a sensitivity of 41.2%, specificity of 98.9%, transverse sinus stenosis sign has a sensitivity of 82.4%, specificity of 88.8%, posterior globe flattening sign has a sensitivity of 21.6%, specificity of 100.0%, Optic nerve head protrusion sign has a sensitivity of 27.5%, specificity of 98.9%, Optic nerve sheath distention, tortuosity sign has a sensitivity of 43.1%, specificity of 96.6% in the detection of IIH cases. Also, it shows that fundus examination has a sensitivity of 52.9%, specificity of 96.6%, in detection of IIH cases. Also, optic nerve sheath diameter assessment through sonography has sensitivity of 66.7%, specificity of 26.7%.
Conclusion: Our study estimated the prevalence of CSF dysregulation headache disorder among headache patients showing that 30.35% of the included patients fulfilled the diagnostic criteria for IIH whereas 69.64% did not. We highlight the importance of neuroimaging signs in IIH as empty sella turcica sign, transverse sinus stenosis sign, flattening of the posterior aspect of the globe, optic nerve head protrusion sign, and optic nerve dilation and tortuosity sign were highly associated with IIH and elevated OP.