الفهرس | Only 14 pages are availabe for public view |
Abstract Keloid and hypertrophic scar are pathologic scarring conditions characterized by fibroblast hyper-proliferation and excess deposition of collagen. Patient frequently experiences physical deformity, restricted range of motion, pruritus and pain. Recent studies reported that Botulinum toxin type A (BTX-A) could inhibit the growth of hypertrophic scars and keloids and improve their appearance. However, the mechanism of BTXA’s action on hypertrophic scars is still unknown. Aim of work: to evaluate the clinical effect of BTX-A on keloids and hypertrophic scars and to detect its effect on collagen deposition and elastic fibers of these scars histopathologically. |