الفهرس | Only 14 pages are availabe for public view |
Abstract Leontodon hispidulus Boiss. (L. hispidulus) is a rare wild plant growing in the Egyptian North Coast. It belongs to the family Asteraceae which is known for its wide variety of active constituents and biological activities. Few work was traced concerning L. hispidulus. Other species of the same genus proved to contain active phenolic compounds and terpenes, and possess anti-inflammatory, cytotoxic as well as antioxidant activities. In the present study, HPLC, LC-qTOF-MS profiling and GC/MS profiling of fatty acids and hydrocarbons were all performed for the first time on this plant. HPLC analysis of the ethanolic extract of L. hispidulus aerial parts revealed that phenolic acids (p-coumaric, chlorogenic, caffeic, vanillic and protocatechuic) and flavonoids (quercetin and kaempferol) were the most abundant phenolic compounds. LC-qTOF-MS profiling of the ethanolic extract allowed the identification of various flavonoids and their glycosides including luteoline, kaempferol, quercetin, apigenin, naringenin, formononetin and acacetin, as well as different phenolic acids as chlorogenic, rosmarinic, coumaric, hydroxybenzoic and caffeic acids. Coumarines as dihydroxycoumarin, daphnetin and esculin were also detected. |