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العنوان
The role of renovascular duplex and serum cystatin c in the prediction of hepatorenal syndrome in critically ill liver cirrhotic patients /
الناشر
Ibrahim Mohamed Abdelazim ,
المؤلف
Ibrahim Mohamed Abdelazim
هيئة الاعداد
باحث / Ibrahim Mohamed Abdelazim
مشرف / Waheed Radwan
مشرف / Mervat Eldamarawy
مشرف / Osama Tayeh
تاريخ النشر
2014
عدد الصفحات
150 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
العناية المركزة والطب العناية المركزة
تاريخ الإجازة
26/5/2015
مكان الإجازة
جامعة القاهرة - كلية الطب - Critical Care Medicine
الفهرس
Only 14 pages are availabe for public view

from 167

from 167

Abstract

Hepatorenal syndrome (HRS) is a 2functional3 and reversible form of renal failure that occurs in patients with advanced chronic liver disease. Doppler ultrasonography is a non - invasive tool for the assessment of vascular patency and has been used to measure hepatic arterial and venous flow in patients with portal hypertension. Several studies have reported that the reciprocal of cystatin C correlates better with GFR than does the reciprocal of creatinine. 40 patients, of whom 10 persons were normal volunteers taken as a control group, group A patients (No. = 20) with liver cirrhosis and normal renal functions had been followed up for an average of 12 months searching for development of hepatorenal syndrome HRS. During the follow up, 5 patients developed HRS, serum cystatin level showed a more statistically significant rise in the same patients with higher P value. Using ROC curves support an advantage of cystatin C over serum creatinine. Using multiple variables in cox regression model, we found that the risk of death is higher if increasing cystatin c with highly significant value (P value 0.001). When used ROC curves for R.I. RI at a level of 0.66 showed 80% sensitivity and 90% specificity