الفهرس | Only 14 pages are availabe for public view |
Abstract Background: About 20% of all intracranial metastases occur in the posterior fossa, 25-50% is single, involving mainly cerebellum, only small percentage (about 2%) of lesions concern brain stem, more rarely pineal region, or cerebellopontine angle. Metastasis in the posterior fossa is poorly tolerated because it can rapidly develop hydrocephalus, brain stem compression, upward transtentorial herniation, so it carries poorer prognosis than supratentorial metastasis, if left untreated. The best treatment options of single metastatic posterior fossa tumors are still debated, with the literature showing benefits of all three major treatment modalities-surgical resection, whole brain radiation (WBR), and stereotactic radiosurgery (SRS). Objectives: The aim of this work was to evaluate the outcome of the surgical resection of single metastatic posterior fossa tumors followed by further adjuvant treatment |