الفهرس | Only 14 pages are availabe for public view |
Abstract Bone substitutes are required to repair osseous defects caused by a number of factors such as trauma, degenerative disease, cancer, and others. Bone tissue engineering seeks to overcome the limitations of conventional therapy by developing alternative therapies that combine three main factors cells, scaffold and growth factors. For bone tissue engineering the scaffold need to exhibit high biocompatibility, bioactivity, adequate mechanical strength and morphological characteristics to achieve bone tissue regeneration. Although several materials have been used in bone tissue engineering most of these materials are still far from completely fulfilling both the necessary biological and mechanical functions. Thus the aim of this study was to prepare and evaluate Portland cement based scaffolds for bone tissue engineering. In this study scaffolds were fabricated by two different routes; the first route was based on producing porosity, through a chemical reaction between fine aluminum powder and calcium oxide in presence of water |