الفهرس 
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Abstract
This study was conducted to compare the effect of psyllium seeds and its husk on hypercholesterolemic rats.
After the period of adaptation, the rats were divided into two main groups. The first main group(n=6) was fed on the basal diet during the experimental period as a negative control group (- ve).the second main group (n=30) was fed basal diet plus cholesterol (1%) and bile salt (0.25%) to induce hypercholesterolemia in rats .These rats were divided into 5 subgroups, as follows: Subgroup (1) rats were fed on high cholesterol diet (as a control positive group). Subgroup (2) rats were fed on high cholesterol diet supplemented with 2.5% Psyllium husk. Subgroup (3) rats were fed on high cholesterol diet supplemented with 5 % Psyllium husk powder. Subgroup (4) rats were fed on high cholesterol diet supplemented with 2.5 % Psyllium seed powder. Subgroup (5) rats were fed on high cholesterol diet supplemented with 5 % Psyllium seed powder.
At the end of the experimental period (8 weeks), rats were starved for 12 hr., blood samples were collected then centrifuged were carried out by determination of feed intake, body weight gain% and feed efficiency ratio. Biochemical analysis of kidney and liver function, lipid profile
1- Effect of psyllium seeds and its husk on body weight status:
The FBW significantly decreased by Psyllium husk in the concentration of 5% that was significantly lower than Psyllium husk in the concentration of 2.5 % more than psyllium seeds compared the control positive group. BWG % was significantly decreased using Psyllium husk specially in the concentration of 5 % than Psyllium seeds either in the concentration of 2.5 or 5 %. Also, FER was significantly decreased by the Psyllium husk in the concentration of 5 % more than Psyllium seeds either in the concentration of 2.5 or 5 %. Feed intake was seen to be lower in the groups consumed Psyllium seeds or husk.
2- Effect of psyillum seeds and its husk on serum liver functions:
AST, ALT, and ALP were found to be significantly decreased by Psyllium husk in the concentration of 5% compared to Psyllium seeds either in the concentration of 2.5 or 5 % in comparison to the control positive group.