![]() | Only 14 pages are availabe for public view |
Abstract Respiratory distress syndrome(RDS)or hyaline membrane disease HMD is a main cause of morbidity and mortality in the early neonatal period. It is most common in infants born at fewer than 28 weeks‟ gestation and affects one third of infants born at 28 to 34 weeks‟ gestation but occurs in less than 5 percent of those born after 34 weeks‟ gestation. RDS is caused by developmental insufficiency of surfactant production and function, as well as by structural immaturity of the lungs. It can also result from surfactant protein genetic disorders.Infants with RDS typically present within the first several hours of life, often immediately after delivery. Clinically, infants have marked respiratory distress with tachypnea, nasal flaring, grunting, and subcostal, intercostal, and/or suprasternal retractions. The basis of treatment for patients who are suffering from RDS is the use of surfactant and respiratory support i.e. Mechanical Ventilation (MV) and Nasal Continuous Positive Airway Pressure (NCPAP). Bronchopulmonary dysplasia can occur in complicated cases, leading to recurrent wheezing, asthma, and higher hospital admission rates later in life. |