الفهرس 
Sleep Quality, Depression and Lipid Profile among Shift Healthcare Workers in Cairo University hospitals
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Abstract
Background: Shift work is considered essential in hospitals for consistently providing excellent service. Although shift work benefits the community, it leads to circadian rhythm disruption, which is linked to health problems such as poor sleep quality, depression, and dyslipidemia.
Aim: To study the sleep quality, depression and lipid profile among shift healthcare workers in Cairo University hospitals.
Subjects and methods: This was a comparative cross-sectional study carried out at Kasr Al-Ainy Hospital, Cairo University, over a period from the beginning of February 2022 to the end of September 2022. The study included 90 healthcare workers who were further classified into (36) day shift group, (24) fixed night shift group, and (30) rotatory shift group. The study group was assessed using a sleep quality questionnaire, the Hamilton depression rating scale, and lipid profile tests including total cholesterol, triglycerides, high density lipoproteins (HDL) and low-density lipoprotein (LDL).
Results: The current study showed that there were statistically significant differences between the rotatory and the day group as regards working hours, total cholesterol, TAG, VLDL, HDL risk factor, non-HDL, Hamilton Depression Rating Scale score, restoration after sleep, difficulty in falling asleep, difficulty in getting sleep, satisfaction with sleep and Total score of sleep quality (p<0.05). There were also highly statistically significant differences between the fixed night and the day groups as regards working hours, heart rate, total cholesterol, LDL, difficulty in falling asleep, satisfaction with sleep, total sleep quality score and the Hamilton Depression Rating scale (p<0.05).
There were statistically significant positive correlations between shift working hours and each of total depression score, total cholesterol, TAG, LDL, non-HDL, VLDL, and HDL risk (p <0.05).
There were statistically significant positive correlations between total sleep score and each of TAG, and LDL, total cholesterol and total depression score (p<0.05).
Statistically significant positive correlations were also found between depression score and each of total cholesterol, TAG, and LDL levels (p<0.05).
Conclusion: The current study showed that shift work had negative impact on sleep quality, mood and lipid profile. Rotatory and fixed-night groups were found to have higher scores for poor sleep quality, depression, and a higher level of lipid profile compared to the day group.Recommendation: Psychological and lipid profile screenings are required at pre-employment and regular periodic medical assessments of healthcare workers. Health programs, especially for shift workers are needed, including psychological intervention programs, nutrition and exercise to decrease the burden of psychological mood disorders. Management of sleep disorders is also essential.