الفهرس 
Clinico-pathological characteristics and treatment outcomes of patients with stage ii colon cancer, single institutional experience
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Abstract
Introduction: Colorectal cancer is the third most commonly diagnosed
cancer worldwide constituting 10 % of total cancer cases, it’s the second
cause of cancer deaths worldwide. In Egypt colorectal cancer is the ninth
most commonly diagnosed cancer.
Surgical resection is the only curative treatment for locoregional colon
cancer. Adjuvant chemotherapy was found to be beneficial in stage III
disease, while in stage II disease its benefit is less certain.
Aim of the Work: Describe the demographics and clinico-pathological
features of patients with stage II colon cancer, whether they received
adjuvant chemotherapy or not and the outcome of this population as a part
of the NCI experience in the period between January 2013 and December
2018.
Patients and Methods: This retrospective cohort study was conducted at
the National Cancer Institute, Cairo University, and included patients
diagnosed with stage II colon cancer in the period from January 2013 to
December 2018.
Results: A total of 89 patients with stage II colon cancer were included
with mean age 50.42 ±13.13 years, 52.8 % were below the age of 50, male
patients represented 58.4%, right sided tumors were present in 57.1% of
patients and 42.9 % were in left colon, adjuvant chemotherapy was given
to 62.8% of patients, Adjuvant chemotherapy was associated with
significant improvement in DFS at 5 years 79.6% vs 62.6% (p 0.036) and
OS 92.6% vs 76.4% (p 0.026) compared to surveillance only.
Conclusion: in our study adjuvant chemotherapy was associated with
better DFS and OS in patients with stage II colon cancer compared to
surveillance only.