الفهرس | Only 14 pages are availabe for public view |
Abstract 1. This is a retrospective, observational study with a relatively small number of patients. 2. QCA and IVUS were not analyzed by an independent core laboratory. 3. The study performed mainly on large epicardial vessels and did not include small branches e.g. diagonal and obtuse marginal branches. This made the cutoff value of MLA proposed by this study not sufficient. 4. The study population was predominantly male (70.0%) presenting mainly with stable angina/asymptomatic therefore we cannot extrapolate our findings to other clinical scenarios (such as acute coronary syndromes). 5. The cutoff points of minimum lumen diameter suggested in our study cannot be applied to lesions with multiple stenosis 6. Hyperemia induced by adenosine in the catheterization laboratory is not necessarily equivalent to exercise-induced maximal hyperemia in daily life. This mechanism could have played a part in the patients with positive exercise tests but FFR values of 0.80 or higher. 7. Clinical outcomes could not be evaluated in this study. The outcomes of FFR- guided versus IVUS-guided revascularization strategy need to be evaluated in future randomized trials. |