الفهرس | Only 14 pages are availabe for public view |
Abstract disease is employed to explain the metabolic syndrome (MetS). Likewise, genetic differences related to metabolic syndrome play a key role in its prevalence and side effects. This study aims to explore the expression of DYRK1B and its association with metabolic syndrome in a small cohort of Egyptian. Materials and methods: A total of 100 adult Egyptians (50 with MetS and 50 healthy control subjects) were incorporated to this study. Clinical, biochemical and anthropometric analysis were evaluated. Relative gene expressions of DYRK1B were compared between two groups of subjects using quantitative real time PCR. Results: The results showed substantial overexpression in DYRK1B (p<0.05) in MetS subjects when compared with the healthy control subjects. Conclusion: This is the first study to impart evidence that DYRK1B is highly expressed among the MetS subjects. |