الفهرس 
Title : Correlation between Serum Progesterone Level on the Day of Ovulation Trigger and Pregnancy Outcomes after Fresh Embryo Transfer in Intracytoplasmic Sperm Injection Cycles
AbstractOnly 14 pages are availabe for public view
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Abstract
Background:
Due to the simultaneous stimulation of a large number of follicles in controlled ovarian stimulation (COS) protocols, there is early release of progesterone in the late follicular phase, leading in asynchronous endometrium and implantation failure in fresh cycles.
Premature luteinization (PL) is an early rise in serum progesterone level on or before the day of ovulation triggers.
PL has an adverse effect on endometrial receptivity; poor endometrial receptivity may be due to premature endometrial maturation which may lead to asynchrony between the embryo and endometrium.
Material and method:
This case control study was conducted at private reproductive medicine center from November 2019 until April 2022. A total of 48 women attended IVF/ICSI unit for ICSI‑fresh ET cycle.
Blood sample was collected for serum progesterone level estimation before ovulation trigger.Collected samples were processed within 8 h of sample collection and serum progesterone was estimated.
Study outcome:
To correlate serum progesterone level on the day of ovulation trigger during ICSI and its effect on treatment outcome.
Results:
The study reported that there were no differences between study groups “positive and negative pregnancy tests” regarding progesterone level at day of trigger 0.81 ± 0.37 vs. 1.26 ± 1.19 ng/mL (p= 0.464).
Conclusion:
In women undergoing ICSI‑fresh ET cycle using either long agonist or antagonist protocols, serum progesterone level on the day of ovulation trigger had no statistically significant effect on chemical pregnancy rates