الفهرس 
Title : Phenotypic and Genotypic characterization of AmpC Beta Lactamases in Acinetobacter Species Isolated from Cairo University Hospitals
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Abstract
Acinetobacter species resistance towards β-lactam antibiotics is mediated by different
classes of β-lactamases production. In the present study, we attempted to detect class
C (AmpC)-producing Acinetobacter isolates by two phenotypic methods (AmpC disk
test with Tris- EDTA and DPT with APB test) and compare them with multiplex PCR
as the gold standard method. The results of the study showed that the prevalence of
AmpC-producing isolates was 68.8% by AmpC disk test, 72.9% by DPT with APB
test, and 79.2% by PCR. The sensitivity of AmpC disk test and DPT with APB test
were 86.8% and 92.1% respectively and the specificity was 100% for both tests. The
most prevalent plasmid-mediated AmpC gene family was CIT.