الفهرس | Only 14 pages are availabe for public view |
Abstract Rheumatoid arthritis (RA) is an autoimmune illness that affects the joints over time. It is characterised by a symmetrical increasing inflammation of the afflicted joints that causes bone erosion, cartilage degradation, and impairment. Initially only a few joints are afflicted, but as the disease progresses, more joints are damaged, and extraarticular symptoms are frequently experienced. RA is one of the most common chronic inflammatory illnesses, with prevalence ranging from 0.4% to 1.3% of the population depending on sex (women are affected two to three times more frequently than males), age (frequency of new RA diagnoses peaks in the sixth decade of life). The importance of prediabetes as a metabolic condition is being recognised more and more. It increases the risk of acquiring many of the pathologies typically linked to diabetes, including diabetic retinopathy, neuropathy, nephropathy, and macrovascular problems, in addition to raising the likelihood that someone may proceed to diabetes in the future. Our study was aiming to discover if there is a relationship between rheumatoid arthritis and prediabetes . This study included 30 patients with RA and 30 healthy controls in which FBS , 2HrPP and HbA1c was measured Results showed that there was a statistical significant difference higher percentage of pre-diabetic patients among case group 29.2% versus 4.2% in control group with p-value 0.04 suggesting that Rheumatoid arthritis has a role as a risk factor for developing both prediabetes and DM occurrence. Further subgroup analysis among cases only showed a statistically significant difference between prediabetic RA patients and normoglycemic ones . |