الفهرس | Only 14 pages are availabe for public view |
Abstract Summary The prevalence of diabetes is increasing rapidly with more than 62 million cases in India. Long-term effects of diabetes include retinopathy, nephropathy and neuropathy. Diabetic foot is a blanket term for foot disorders such as infection, ulceration or destruction of deep tissues due to peripheral neuropathy and ischemia from peripheral vascular disease .The diabetic foot ulcers take time to heal and require great care. Offloading and debridement of the wound expedites the healing process, however in wounds of advanced grade and stage vascular repair or amputation might be required. At least 40% of these amputations can be prevented with a team approach to wound care. The selection of wound dressings plays a pivotal role in diabetic wound care management. Nano-crystalline silver ion dressing is an effective antimicrobial barrier composed of an absorbent inner core that maintains a moist environment optimal for wound healing and outer layers of silver coated polyethylene nets which prevent wound contamination and exhibit bactericidal effect. Nano-crystalline silver ion dressings have been in use for burns and chronic wounds, but the literature on their use in diabetic wounds is limited. In the current study we aimed to study the effect of the Tetra-Silver nano-particle on wound management according to wound stage and its effect on diabetic foot ulcer and its healing and comparing with saline followed by povidone iodine. The enrolled patients were randomized into 2 groups. group 1(dressing with tetra-silver nanoparticle):52 patients were submitted to dressing with Tetra-Silver after washing the ulcer by distilled water .group 2(conventional dressing group): 52 patients undergo dressing with ordinary dressing (e.g. saline followed by povidone iodine.) In this study, there were insignificant differences between two groups as regard demographic data In this study, there was insignificant differences between two groups as regard insulin therapy and Oral hypoglycemic medications, as regard laboratory data there was insignificant differences between two groups as regard HBA1c, Hb(g/dl) and Albumin (g/dl) In this study, there were insignificant differences between two groups as regard Duration of DM (years) In this study, there were significant differences between two groups with higher healing area in group I in 2nd week and 4th week but after that there were insignificant differences between two groups. |