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Abstract Purpose: To test the safety and the efficacy of full endoscopic discectomy as compared to the gold standard mini-open fenestration discectomy. Methods: This study is a prospective study for patients with Lumbo-Sacral disc herniation treated with discectomy either mini-open or endoscopic. 36 patients were included in this study, group 1 was operated by mini-open fenestration discectomy and group 2 was operated using full endoscopic discectomy. Both techniques will be compared as regards the operative data, the functional outcome of the patients and the complications. where Pain is assesed using Visual Analogue score (VAS) and Functional outcome of the patients is assessed using Oswestry disability index (ODI) and modified MacNab criteria Results: In this study 36 patients were operated (20 for fenestration discectomy and 16 for full endoscopic discectomy). The mean age was 34.9 in group1 and 31.6 in group 2, group 2 has more female percentage within the group (50%) than group 1 (15%) ,L5/S1 level was dominant in group 1 (55 %). And L4/5 was dominant in group 2 (56.2%).The mean operative time was 58 mins in group 1 and 62.5 mins in group 2.Both groups had the same hospital stay. Patients in both groups showed significant improvement in their functional outcomes and comparable rate of complications. Conclusion:This study showed that full endoscopic discectomy is an effective method for operative management of Lumbo-Sacral disc herniation. It is as safe and effective as the gold standard mini-open fenestration discectomy with comparable functional improvement of the patients.Full endoscopic discectomy was superior to the mini-open fenestration discectomy in terms of faster recovery, earlier return towork, smaller incision and minimal bloss loss |