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Abstract Summary 83 Summary Enteral feeding intolerance is defined as the failure to provide sufficient EN to critically ill patients due to delay of gastric emptying with the absence of mechanical blocking (Elmokadem et al., 2021). It may affect the effectiveness of enteral feeding, thereby prolonging hospital stay and increasing mortality rate. So, the aim of this study is to investigate tube feeding intolerance among critically ill patients at Assiut University Hospital. The design of this study was a descriptive exploratory survey research design. This study was conducted at general, trauma, coronary, anesthesia, and Alraghi intensive care units at Assiut University Hospital, Egypt. A purposive sample of 65 adult male and female critically ill patients receiving enteral feeding within 24-48 hours of their admission to the intensive care unit and participated in study with the following inclusion criteria as patient with age ranged between 18-60 years and exclusion criteria as patients with hemodynamic instability, uncontrolled shock, uncontrolled life-threatening hypoxemia, hypercapnia, or acidosis, active GI bleeding, bowel discontinuity, overt bowel ischemia, abdominal compartment syndrome, high output intestinal fistula, continued obstruction of the GI tract, gastric residual volume >500 mL/6hrs, brain death, stomach cancer, abdominal trauma, osophageal varices and delayed initiation of EN (>48 hours) in the absence of contraindication to EN and they were excluded from the study. Four tools were utilized to collect data, which are: Tool I: Adult critically ill tube feeding intolerance manifestations assessment sheet. Tool II: Nutrition status assessment tool by using The Mini Nutritional Assessment Short-Form. Tool III: Enteral feeding intolerance risk factors assessment sheet. Tool IV: Adult critically ill tube feeding intolerance complications assessment Summary 84 sheet. A pilot study carried out in order to assess the feasibility and applicability of the tools and the necessary modifications were done. The pilot study was done on 7 patients were included in the study. The main results:- The mean age of studied sample was (36.57±10.34); about (33.8%) of patients their age ranged from 40 - < 50 yrs. and (55.4%) were males. The majority of patients (84.6%) manifested by equal to or more than two symptoms of enteral feeding intolerance. Results revealed that pain, stress, bed rest, use of broad-spectrum antibiotics were common risks for enteral feeding intolerance for all patients (100%). The majority of patients (90.8%) took sedative or analgesic agents and had hypoproteinemia, (83.1%) were connected with mechanical ventilator, but age >60 yrs., abdominal surgery and acute/severe pancreatitis weren’t matched in studied sample (0%). Results clarified that more than two thirds of patients suffered from vomiting, constipation, flatulence, abdominal distention and straining {(69.2) (69.2) (66.2) (64.6) (64.6)} respectively while more than one third of patients (32.3%) suffered from diarrhea. There was positive correlation between patient’s age and frequency of tube feeding intolerance with statistical significance; p values (0.045*). Results showed that the majority of patients (83.1%) were connected with mechanical ventilator, more than two thirds of patients |