الفهرس | Only 14 pages are availabe for public view |
Abstract Background and rationale: Trauma of tracheal intubation and manipulation of airway especially after neck cancer surgeries increase the risk of post operative airway edema. Both mannitol and corticosteroids are effective in reducing airway edema but mannitol is more favourable by avoiding side effects of corticosteroids and less reported complications with mannitol. This study was carried out to evaluate and compare the effect of mannitol and corticosteroids in reducing airway edema following neck cancer surgeries . Methodology We studied 56 patients underwent thyroidectomy and neck dissection operations for cancer neck. The patients divided into 2 groups (n=28) where the first group received 0.25 gm/kg mannitol 30 minutes before induction of anesthesia and before end of surgery, the second group received hydrocortisone 3 mg/kg 30 minutes before induction and after 3 hours with lengthy operations. Cuff leak test, post extubation edema and hyperemia,incidence of airway obstruction and complications in the form of gastritis, hyperglycemia and electrolytes imbalance were recorded. Results: The incidence of post extubation edema and airway obstruction in mannitol group (3 patients out of 28) but in steroid group (5 patients out of 28). Airway obstruction was partial and responded to medical treatment and no patients needed reintubation. Complications of treatment in the form of hyperglycemia and gastritis were reported in six patients of the steroid group but statistically was insignificant |