الفهرس | Only 14 pages are availabe for public view |
Abstract Androgenetic alopecia (AGA) is the most common pattern of loss of scalp hair in both men and women. The hair loss appears to be caused by a combination of genetic predisposition and hormonal triggers. These lead to shortening of the anagen phase of the hair cycle and miniaturization of the hair follicle, eventually resulting in transformation of the hair follicle from one capable of producing long terminal pigmented hairs to one that produces only short fine vellus hair. Such transformations occur in a programmed pattern across particular regions of the scalp, resulting in a characteristic balding pattern. Androgenetic alopecia is defined as a chronic, diffuse, progressive hair loss. Patients have hair loss in a ratio of 2 : 1, that is, for every 2 new hair threads; one is lost. The hair loss usually begins between the ages of 12 and 40 years and is frequently insufficient to be noticed. However, visible hair loss occurs in approximately one half of all persons by the age of 50 years. Female Pattern Hair Loss (FPHL) has emerged as the preferred term for androgenic alopecia in females owing to the uncertain relationship between androgens and this entity. It is characterized by a reduction in hair density over the crown and frontal scalp with retention of the frontal hairline. Summary and conclusion 69 Usually, women do not suffer classic male pattern baldness. In women, the hair becomes thinner all over the head, and the hairline does not recede. This is called ”Female pattern baldness” and may occur in males. This variety of androgenic alopecia in women rarely leads to total baldness. Hair loss in women is associated with significant psychological morbidity suggested that women place a greater emphasis than men on physical appearances and outward attractiveness. Hair is an essential part of a woman’s sexuality and gender identity, and any hair loss generates feelings of low selfesteem and anxiety from a perception of diminished attractiveness. The clinical picture of typical Female Pattern Hair Loss (FPHL) begins with a specific ”diffuse loss of hair from the parietal or frontovertical areas with an intact frontal hairline”; this process ”rarefaction”. In Ludwig’s classification of hair loss in women, progressive type of FAGA, 3 patterns were described: grade I or minimal, grade II or moderate, and grade III or severe. Studies have determined relatively Increased risk of coronary heart disease (CHD) in Androgentic alopecia (AGA). They revealed a meaningful association between AGA and hyperlipidemia. Androgentic alopecia associated with significantly increase total cholesterol and LDL-cholesterol. Furthermore, studies have shown that the pattern of lipid profile of patients with AGA predisposes them to CAD. Summary and conclusion 71 There is a correlation between androgenic alopecia (AGA) and life-threatening diseases, such as coronary artery disease (CAD). The frequency of CAD has been shown to increase in AGA. The relationship of CAD with AGA has been demonstrated, but few studies have focused on the mechanism of this association. Few studies have focused on this association in females with AGA and dyslipidemia that be considered as a risk factor for many threatening life diseases. Female Androgenetic Alopecia, like male pattern baldness, was associated with CAD in women younger than 55 years. Dermatologists should investigate the lipid parameters, especially total cholesterol and LDL-cholesterol in female patients AGA as evaluative measure. The aim of this study was to detect correlation between the |