الفهرس | Only 14 pages are availabe for public view |
Abstract The volatile compounds of the aerial parts and flowers of Plectranthus neochilus Schltr. and Salvia farinacea Benth. were studied using headspace solid phase micro-extraction. This study revealed that the major compounds in the aerial parts of Plectranthus neochilus Schltr. were found to be allo-aromadendrene (19.35 %), aromadendrene (18.3 %) followed by selina-3,7(11)-diene (10.2 %), while Þ- cadinene (18.56 %) and aromadendrene (17.94 %) followed by Ý-myrcene (10.5 %) and E-Ý-ocimene (9.11 %) were the major components of the flowers. Regarding Salvia farinacea Benth., 1-octen-3-ol was found as the major component in the aerial parts, whereas ethyl benzene was the abundant component found in the flowers. UPLC-HRMS revealed the presence of 21 and 18 chromatographic peaks in the flowering aerial parts of Plectranthus neochilus Schltr. and Salvia farinacea Benth., respectively. Biologically guided study of the flowering aerial parts of both plants revealed that the methylene chloride fraction of Plectranthus neochilus Schltr. and the n-butanol fraction of Salvia farinacea Benth. were the most active fractions regarding the in-vitro anti-inflammatory activity that measured the effect of the different extracts and fractions of both plants on the gene expression of the pro-inflammatory cytokines and enzymes |