الفهرس 
Some pharmacological and toxicological studies on some constituents of apricot seeds
AbstractOnly 14 pages are availabe for public view
 |  | from | 215 |  |  |
| | | from | 215 | | |
Abstract
The present study aimed to investigate some phytochemical, toxicological and pharmacological activities of ethanolic apricot seeds extracts. Different phytochemicals were analyzed. The phytochemical screening was done for determination of total phenolic compounds by Folin{u2013}Ciocalteu method, total flavonoids by aluminum chloride colorimetric method, total carotenoids by colorimetric method and amygdalin content by using HPLC. The anti-inflammatory activity and total antioxidant capacity of the extracts were done. The anti-inflammatory activity was done in vitro by determination of the half maximal inhibitory concentration (IC50) values for inhibition of the enzymes cyclooxygenase 1, 2 (COX-1, COX-2). The total antioxidant capacity was determined by determination of DPPH (1, 1-diphenyl-2-picryl-hydrazyl) radical scavenging activity. The in-vitro cytotoxicity of extracts on normal human lung cell line and liver cancer cells (HepG2) was determined. The toxicological studies (Acute toxicity) of 70% and 99.9% ethanolic extracts were investigated