الفهرس 
Omega 3 supplementation in children with idiopathic generalized epilepsy
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Abstract
Background: Idiopathic generalized epilepsy (IGE) is a group of epileptic disorders that are believed to have a strong underlying genetic basis. Patients with an IGE subtype are typically otherwise normal and have no structural brain abnormalities. People also often have a family history of epilepsy and seem to have a genetically predisposed risk of seizures. Omega-3 fatty acids-also called }-3 fatty acids or n-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond (C=C) at the third carbon atom from the end of the carbon chain. Omega 3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. Studies indicate that low-dose fish oil may reduce seizures and improve the health of people with epilepsy. Aim of the work: Assessment of role of omega 3 supplementation in children with idiopathic generalized epilepsy. Patients and methods: This prospective single blinded randomized controlled clinical trial study was conducted on 90 children with idiopathic generalized epilepsy following at neurology outpatient clinic or admitted at Abo el-resh Pediatric Hospital Cairo University. June 2015 to June 2017. Results: Analysis was performed in terms of Seizure frequency was evaluated by recording the number of epileptic attack per month using a diary given to the parents who had to register the number of seizure attacks each day. Seizure severity was assessed by the National Hospital Seizure Severity Scale (NHS3). Our results showed that relation between omega 3 high dose and duration of seizure is significant (P Value = 0.015) compared to placebo group and seizure frequency is significant also (P Value= 0.009), relation between omega 3 high and low dose and seizure frequency use is significant P Value = 0.01