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Abstract Background: NAFLD is the most common liver disease. Several studies showed an association between NAFLD and coronary artery disease. Coronary CT angiography permits detection and characterization of coronary plaques. High-risk plaque features are associated with acute coronary syndrome and future adverse cardiovascular events.The aim of this study is to determine the association between nonalcoholic fatty liver disease (NAFLD) and the presence of high-risk coronary atherosclerotic plaque as assessed with coronary computed tomographic (CT) angiography. Methods: This study included 800 patients who had been evaluated consecutively using 64-slice MDCT because of suspected CAD. Readers assessed coronary CT angiography images for the presence of coronary plaque, coronary stenosis, and high-risk plaque features (positive remodeling, CTattenuation > 30 HU, napkin-ring sign, and spotty calcium). NAFLD was defined as hepatic steatosis at non-enhanced CT (liver minus spleen CT attenuation> 1 HU) without evidence of clinical liver disease, liver cirrhosis, or alcohol abuse |