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Abstract from this study, the followings were concluded: Preformed class I & II DSAs may turn to negative post-TX but they become deleterious if they persist after TX in high titre. De novo development of DSAs occurs even recipients are non-sensitized at TX time or even getting proper pre-TX desensitization program The frequency of post-TX total IgG, IgG1and IgG3 levels increased mainly 24-36 months post-TX, so recipients should be routinely evaluated for DSA classes and subclasses at this period but their effect in graft outcome was unclear The incidence of post COVID-19 DSA, acute rejection and graft loss was not changed during the COVID-19 pandemic No rejection occurred despite of increased frequency of high total IgG, IgG1 and IgG3 and positive Class I & II PRA in Covid 19 infected recipients. |