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Abstract Background and objectives Fascia Iliaca Compartment Block has been established as good procedure for Pain control in pediatrics undergoing split thickness skin graft , in multiple trials for better analgesia many additives has been used perineurallyDexamethasone has been used as additive in many peripheral nerve blocks and showed good effect in prolongation of block duration . also it shows analgesic effect when administrated intravenously In this study , we compared which has better analgesic effect Dexamethasone perineural or intravenous route . Design: double blinded randomized controlled trialSetting: Assiut University Hospitals Patients and Methods: 60 pediatric patients undergoing split thickness skin graft allocated into two equal groups. group V each one will receive US guided fascia-iliaca block with 0.7 ml/kg of bupivacaine 0.25% plus 2 ml of normal saline perinural plus 0.15 mg/kg dexamethasone (maximum of 4 mg) in 2 ml volume intravenously, and group N each one will receive US guided fascia-iliaca block with 0.7 ml/kg of bupivacaine 0.25% plus 0.15 mg/kg dexamethasone (maximum of 4 mg) in 2 ml volume perinural plus 2 ml of normal saline intravenously.Inclusion criteria are children from2 to 12 years old, ASA I-II , Scheduled for split thickness grafting . Summary, Conclusion, And Recommendation Exclusion criteria are Patient’s guardian refusal to participate in the study ,Known allergy to local anesthetics ,Children known to be diabetic,Coagulopathy, Children with motor or sensory deficits in lower extremities,Children who are morbidly obese (BMI≥30) because ultrasound guided regional anesthesia could be too technically difficult. |