الفهرس | Only 14 pages are availabe for public view |
Abstract Objective: To investigate the effect of preoperative ultrasound guided stellate ganglion block with local anesthetic on the incidence of neuropathic pain following mastectomy for breast cancer. Patients and Methods: Following approval of the ethics committee (IRB number 00004025) and registration with clinical trial.gov number (NCT 04238377), eighty patients scheduled for mastectomy with axillary dissection were included in the study. Patients were randomized into two equal groups: (group A, stellate) received preoperative ultrasound guided stellate ganglion block and multimodal systemic analgesia, (group B, control) received multimodal systemic analgesia only. Patients were followed for 6 months for neuropathic pain using grading system for neuropathic pain (GSNP).Assessment of patient daily activity & functional capacity was evaluated using Eastern Cooperative Oncology group (ECOG) scoring. In addition, postoperative opioid consumption in the first 24 hours was documented. Results: The 6-month relative frequency of neuropathic pain syndromes, shows statistically significance lower frequency in group A than group B. Postoperative opioid consumption and visual analogue score (VAS) score were significantly lower in group A than in group B with average VAS 3.5 and 5.5 respectively. Assessment of patient daily activity & functional capacity were significantly better in group A than group B |