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العنوان
Study on the possible protective effects of some drugs and natural agents on experimentally induced dementia in rats /
الناشر
Nada Gamal Abdelfattah Elsamahy ,
المؤلف
Nada Gamal Abdelfattah Elsamahy
هيئة الاعداد
باحث / Nada Gamal Abdelfattah Elsamahy
مشرف / Mohamed Tawfik AbdelAziz
مشرف / Mohammed Farag ElYamany
مشرف / May Ahmed Galal AbdelFattah
تاريخ النشر
2020
عدد الصفحات
168 P . :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
15/10/2020
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmacology and Toxicology
الفهرس
Only 14 pages are availabe for public view

from 210

from 210

Abstract

Dementia is a syndrome of global cognitive decline which intervenes with social and occupational functioning. It is common in the elderly and constitutes one of the largest burdens for individuals and society.The most common types of dementia are Alzheimer{u2018}s disease (AD), caused by neurodegeneration and vascular dementia,caused by cerebrovascular disease. Although the primary cause of AD remains unclear, A{uF062} and tau protein aggregation, reduced acetylcholine (Ach) as well as glutamate excitotoxicity may be considered principal pathogenic factors. Many studies have speculated that free radicals produced during oxidative stress and/or inflammatory processes are also involved in progression of AD