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Abstract Back ground: chronic obstructive pulmonary disease (COPD) is a rising major problem. Dyspnea causes reduction of functional status and quality of life in it. Pursed lips Breathing (PLB) and mouth mask were used to reduce dyspnea and improve quality of life. Aim of study: To compare the effect of mouth mask versus pursed lip breathing on ventilatory functions and dyspnea index in COPD patients Methods: Forty COPD men patients (FEV 1/FVC <0.70) were selected from outpatient clinic at Chest Department Kasr El-Ainy Hospital, age ranged from 50-65 years old. Ventilatory functions, Dyspnea index, oxygen saturation,CAT score questionnaire, were measured pre and post training program. Patients were assigned in two groups equal in number. group (A): consisted of 20 patients were treated by expiratory breathing through Mouth Mask plus routine chest physiotherapy. group (B) consisted of 20 patients were treated by pursed lip breathing plus routine chest physiotherapy . For both groups, the Program was for five days per week for 8weeks Results:There was a significant increase in FVC, FEV1, FEV1/FVC, PEF and FEF25-75 in both groups with a percent of improvement 19.25%, 44.29%, 21.5%,38.28%and 71.58% respectively in the group A and 8.7%, 18.37%,8.9% ,21.2% and 28.75% respectively in group B (p > 0.001) with more improvement in group A. There was a significant decrease in CAT score with a percent of improvement 61.07% and 46.07% respectively in the group A and B (p >0.001) There was a significant decrease in DI pre and post 3 min step test post treatment in the group A and B with more improvement in group A (p >0.0001).There was a significant increase in oxygen saturation pre and post 3 min step test with a mean difference between both groups A&B .75% pre 3min step test and 1.15% post 3min step test |