الفهرس | Only 14 pages are availabe for public view |
Abstract Necrotizing enterocolitis (NEC) is a severe neonatal gastrointestinal disease with high morbidity and mortality, characterized by intestinal cell damage and inflammation.NEC results from combination of several factors, including genetic predisposition, intestinal immaturity, excessive intestinal in{uFB02}ammatory response, and inappropriate microbial colonization.Because NEC is characterized by loss of bowel wall integrity, intestinal fatty acid-binding protein (I-FABP) is one of the more promising biomarkers.This small cytosolic protein, located mainly in enterocytes of the small intestine, is released into the blood stream after cell disruption.In this study, we aimed to investigate the value of serum I-FABP in early diagnosis and predicting severity of NEC |