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Abstract Recruitment and development of multiple follicles in response to gonadotropin stimulation are the key factors leading to a successful outcome of IVF/embryo transfer treatment. Poor ovarian response may be associated with poor pregnancy rates and many of these cycles are cancelled without proceeding to oocyte retrieval ²,³. On the other hand, exaggerated ovarian response leads to an increased risk of ovarian hyper stimulation syndrome (OHSS)⁴ and the resulting high serum estradiol (E2) concentrations may adversely affect the outcomes of the IVF treatment⁵ also currently applied standard IVF protocols are expensive, and complex so Prediction of ovarian responses prior to stimulation is useful in counseling patients and may be helpful in tailoring the dosage of gonadotropin to individual patients⁶ |